Involvement of lipid peroxide on cycloheximide-induced amnesia in rat.

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چکیده

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Effects of San-yu-tang on the Cycloheximide-induced Amnesia in Rats

The effects of San-Yu-Tang (SYT) on cycloheximide (CXM)-induced amnesia were assessed by passive avoidance in rats. Oral SYT administration (0.5 or 1 g/kg for 1 week) significantly prolonged step-through latency in the amnesic animals. This beneficial effect of SYT on CXM-induced amnesia was enhanced by 8-OH-DPAT (a partial agonist of the 5-HT1A receptor), but reduced by scopolamine (a muscarin...

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Involvement of central amygdala muscarinic receptors in morphine-induced amnesia in rat

Introduction: Learning and memory processes result from interaction of neurotransmitter systems in various brain regions such as amygdala and hippocampus. Considering that morphine induces memory impairment, in the current study, we examined the possible role of cholinergic muscarinic receptor s of the central amygdala (CeA) on the morphine-induced amnesia in adult male Wistar rats. Methods: A ...

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ژورنال

عنوان ژورنال: Japanese Journal of Pharmacology

سال: 1991

ISSN: 0021-5198

DOI: 10.1016/s0021-5198(19)38652-4